A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function

Background: Brown adipose tissue (BAT) is an important tissue for thermogenesis, making it a potential target to decrease the risks of obesity, type 2 diabetes, and cardiovascular disease, and recent studies have also identified BAT as an endocrine organ. Although BAT has been implicated to be prote...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2021-01, Vol.143 (2), p.145-159
Hauptverfasser:	Pinckard, Kelsey M., Shettigar, Vikram K., Wright, Katherine R., Abay, Eaman, Baer, Lisa A., Vidal, Pablo, Dewal, Revati S., Das, Devleena, Duarte-Sanmiguel, Silvia, Hernández-Saavedra, Diego, Arts, Peter J., Lehnig, Adam C., Bussberg, Valerie, Narain, Niven R., Kiebish, Michael A., Yi, Fanchao, Sparks, Lauren M., Goodpaster, Bret H., Smith, Steven R., Pratley, Richard E., Lewandowski, E. Douglas, Raman, Subha V., Wold, Loren E., Gallego-Perez, Daniel, Coen, Paul M., Ziolo, Mark T., Stanford, Kristin I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - metabolism Adipose Tissue, Brown - transplantation Aged Animals Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology Cells, Cultured Cohort Studies Female Heart Failure - metabolism Heart Failure - therapy Humans Life Sciences & Biomedicine Lipidomics - methods Male Mice Mice, Inbred C57BL Middle Aged Oleic Acids - administration & dosage Oleic Acids - metabolism Peripheral Vascular Disease Physical Conditioning, Animal - methods Physical Conditioning, Animal - physiology Science & Technology
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