Advances in the Design of (Nano)Formulations for Delivery of Antisense Oligonucleotides and Small Interfering RNA: Focus on the Central Nervous System

RNA-based therapeutics have emerged as one of the most powerful therapeutic options used for the modulation of gene/protein expression and gene editing with the potential to treat neurodegenerative diseases. However, the delivery of nucleic acids to the central nervous system (CNS), in particular by...

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Veröffentlicht in:Molecular pharmaceutics 2021-04, Vol.18 (4), p.1491-1506
Hauptverfasser: Mendonça, Monique C. P, Kont, Ayse, Aburto, Maria Rodriguez, Cryan, John F, O’Driscoll, Caitriona M
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Sprache:eng
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