Faster fertilization and cleavage kinetics reflect competence to achieve a live birth after intracytoplasmic sperm injection, but this association fades with maternal age

Faster fertilization and cleavage kinetics reflect competence to achieve a live birth after intracytoplasmic sperm injection, but this association fades with maternal age

To assess the relationship of early developmental kinetics with competence to provide a live birth and the impact of maternal age in this context. Retrospective cohort study including 4,915 embryos, of which 1,390 were transferred and provided a clinical outcome paired with morphokinetic data; 168 o...

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Veröffentlicht in:Fertility and sterility 2021-03, Vol.115 (3), p.665-672
Hauptverfasser: Dal Canto, Mariabeatrice, Bartolacci, Alessandro, Turchi, Diana, Pignataro, Daniela, Lain, Monia, De Ponti, Elena, Brigante, Claudio, Mignini Renzini, Mario, Buratini, Jose
Format: Artikel
Sprache:eng
Schlagworte:
embryonic morphokinetics
ICSI
Life Sciences & Biomedicine
live birth
maternal age
Obstetrics & Gynecology
Reproductive Biology
Science & Technology
Time lapse
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Zusammenfassung:To assess the relationship of early developmental kinetics with competence to provide a live birth and the impact of maternal age in this context. Retrospective cohort study including 4,915 embryos, of which 1,390 were transferred and provided a clinical outcome paired with morphokinetic data; 168 of them resulted in a live birth (LB), and 1,222 did not (NLB). Early morphokinetic parameters were compared between LB and NLB embryos from patients stratified into two age groups (
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2020.06.023