Silencing Osteopontin Expression Inhibits Proliferation, Invasion and Induce Altered Protein Expression in Melanoma Cells

Osteopontin (OPN) is a multifunctional phosphoprotein that is expressed in different types of cancers, including melanoma. OPN overexpression is associated with tumor progression and metastasis formation; however, the role of OPN in cell invasion and metastasis formation is not completely understood...

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Veröffentlicht in:	Pathology oncology research 2021-03, Vol.27, p.581395-581395, Article 581395
Hauptverfasser:	Kiss, Timea, Jambor, Krisztina, Koroknai, Viktoria, Szasz, Istvan, Bardos, Helga, Mokanszki, Attila, Adany, Roza, Balazs, Margit
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell growth Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Drug development Experiments Gene Expression Gene Expression Regulation, Neoplastic Gene Silencing Humans Life Sciences & Biomedicine Melanoma Melanoma - genetics Melanoma - metabolism Melanoma - pathology Metastasis Oncology Osteopontin - genetics Osteopontin - metabolism Pathology Pathology & Oncology Research Protein expression Protein Interaction Maps Proteins Reagents RNA, Small Interfering - genetics Science & Technology Signal Transduction - genetics Skin cancer Software Statistical analysis Tumors
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