Enhanced Shear Force Responsiveness of Epithelial Na+ Channel's (ENaC) delta Subunit Following the Insertion of N-Glycosylation Motifs Relies on the Extracellular Matrix

Members of the Degenerin/epithelial Na+ channel (ENaC) protein family and the extracellular cell matrix (ECM) form a mechanosensitive complex. A core feature of this complex are tethers, which connect the channel with the ECM, however, knowledge about the nature of these tethers is scarce. N-glycans...

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