Improving the genistein oral bioavailability via its formulation into the metal-organic framework MIL-100(Fe)

Despite the interesting chemopreventive, antioxidant and antiangiogenic effects of the natural bioflavonoid genistein (GEN), its low aqueous solubility and bioavailability make it necessary to administer it using a suitable drug carrier system. Nanometric porous metal-organic frameworks (nanoMOFs) a...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2021-03, Vol.9 (9), p.2233-2239
Hauptverfasser:	Botet-Carreras, Adria, Tamames-Tabar, Cristina, Salles, Fabrice, Rojas, Sara, Imbuluzqueta, Edurne, Lana, Hugo, Jose Blanco-Prieto, Maria, Horcajada, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiangiogenics Antioxidants Bioavailability Biocompatibility Chemical Sciences Computer applications Drug carriers Drug delivery Encapsulation Galenic pharmacology Genistein Iron Life Sciences Material chemistry Materials Science Materials Science, Biomaterials Metal-organic frameworks Nanoparticles Oral administration Pharmaceutical sciences Pharmacokinetics Science & Technology Technology
Online-Zugang:	Volltext
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