Vibrational Spectroscopic Detection of a Single Virus by Mid-Infrared Photothermal Microscopy

We report a confocal interferometric mid-infrared photothermal (MIP) microscope for ultra-sensitive and spatially resolved chemical imaging of individual viruses. The interferometric scattering principle is applied to detect the very weak photothermal signal induced by infrared absorption of chemica...

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Veröffentlicht in:	Analytical chemistry (Washington) 2021-03, Vol.93 (8), p.4100-4107
Hauptverfasser:	Zhang, Yi, Yurdakul, Celalettin, Devaux, Alexander J, Wang, Le, Xu, Xiaoji G, Connor, John H, Ünlü, M. Selim, Cheng, Ji-Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Bonding strength Chemical bonds Chemistry Chemistry, Analytical DNA Viruses Infrared absorption Interferometry Microscopy Nanoparticles Physical Sciences Predictive control Science & Technology Spectrum Analysis Stomatitis Vibration Vibrations Viruses
Online-Zugang:	Volltext
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