A rapid, antibiotic susceptibility test for multidrug-resistant, Gram-negative bacterial uropathogens using the biochemical assay, DETECT

The increasing prevalence of extended spectrum β-lactamases (ESBLs) and plasmid-mediated AmpC (pAmpC) β-lactamases among Enterobacterales threatens our ability to treat urinary tract infections (UTIs). These organisms are resistant to most β-lactam antibiotics and are frequently multidrug-resistant...

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Veröffentlicht in:	Journal of microbiological methods 2021-03, Vol.182, p.106160-106160, Article 106160
Hauptverfasser:	Jackson, Nicole, Borges, Clarissa A., Tarlton, Nicole J., Resendez, Angel, Milton, Aubrianne K., de Boer, Tara R., Butcher, Cheyenne R., Murthy, Niren, Riley, Lee W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic resistance Antimicrobial susceptibility testing Bacterial Proteins - metabolism beta-Lactamases - metabolism Biochemical Research Methods Biochemistry & Molecular Biology Drug Resistance, Multiple, Bacterial Escherichia coli - isolation & purification Escherichia coli - metabolism Escherichia coli Infections - microbiology Extended-spectrum β-lactamase Humans Infectious disease diagnostics Klebsiella Infections - microbiology Klebsiella pneumoniae - isolation & purification Klebsiella pneumoniae - metabolism Life Sciences & Biomedicine Microbiology Proof of Concept Study Science & Technology Urinary tract infection Urinary Tract Infections - microbiology
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