Circulating mitochondria! DNA is an early indicator of severe illness and mortality from COVID-19

BACKGROUND. Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could be used to predict the risk of poor COVID-19 outcomes remains undetermined. METHODS. We measured circulating MT-DNA levels in...

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Veröffentlicht in:	JCI insight 2021-02, Vol.6 (4), Article 143299
Hauptverfasser:	Scozzi, Davide, Cano, Marlene, Ma, Lina, Zhou, Dequan, Zhu, Ji Hong, O'Halloran, Jane A., Goss, Charles, Rauseo, Adriana M., Liu, Zhiyi, Sahu, Sanjaya K., Peritore, Valentina, Rocco, Monica, Ricci, Alberto, Amodeo, Rachele, Aimati, Laura, Ibrahim, Mohsen, Hachem, Ramsey, Kreisel, Daniel, Mudd, Philip A., Kulkarni, Hrishikesh S., Gelman, Andrew E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences & Biomedicine Medicine, Research & Experimental Research & Experimental Medicine Science & Technology
Online-Zugang:	Volltext
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