AMPK alpha 1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism

We have previously demonstrated that systemic AMP-activated protein kinase alpha 1 (AMPK alpha 1) invalidation enhanced adverse LV remodelling by increasing fibroblast proliferation, while myodifferentiation and scar maturation were impaired. We thus hypothesised that fibroblastic AMPK alpha 1 was a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Basic research in cardiology 2021-02, Vol.116 (1), Article 10
Hauptverfasser:	Dufeys, Cecile, Daskalopoulos, Evangelos-Panagiotis, Castanares-Zapatero, Diego, Conway, Simon J., Ginion, Audrey, Bouzin, Caroline, Ambroise, Jerome, Bearzatto, Bertrand, Gala, Jean-Luc, Heymans, Stephane, Papageorgiou, Anna-Pia, Vinckier, Stefan, Cumps, Julien, Balligand, Jean-Luc, Vanhaverbeke, Maarten, Sinnaeve, Peter, Janssens, Stefan, Bertrand, Luc, Beauloye, Christophe, Horman, Sandrine
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac & Cardiovascular Systems Cardiovascular System & Cardiology Life Sciences & Biomedicine Science & Technology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!