The intervention effect of nicotine on cervical fibroblast-myofibroblast differentiation in lipopolysaccharide-induced preterm birth model through activating the TGF-beta 1/Smad3 pathway

Currently, the clinical treatment of preterm birth, mainly using uterine contraction inhibitors, does not fundamentally reduce the incidence of premature birth (PTB). Premature cervical ripening is an important factor in PTB. We previously found that nicotine-treated pregnant murine had significant...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2021-02, Vol.134, Article 111135
Hauptverfasser: Han, Xinjia, Cai, Chunfang, Huang, Jiezhen, Li, Qiufen, Huang, Liu, Xuan, Qingshan, Yang, Jinying
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Sprache:eng
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