Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development

Organ cell diversity depends on binary cell-fate decisions mediated by the Notch signalling pathway during development and tissue homeostasis. A clear example is the series of binary cell-fate decisions that take place during asymmetric cell divisions that give rise to the sensory organs of Drosophi...

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Veröffentlicht in:	Scientific reports 2020-12, Vol.10 (1), p.21731-21731, Article 21731
Hauptverfasser:	Medina-Yáñez, Ignacio, Olivares, Gonzalo H., Vega-Macaya, Franco, Mlodzik, Marek, Olguín, Patricio
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136 631/136/142 631/208 631/208/135 631/208/2490 631/80 631/80/313 631/80/86 631/80/86/2365 631/80/86/820 Acids Adaptor Protein Complex 2 - physiology Animals Asymmetric Cell Division Cell activation Drosophila - cytology Drosophila - embryology Drosophila - genetics Drosophila Proteins - metabolism Drosophila Proteins - physiology Endocytosis Endocytosis - physiology Endosomes Endosomes - metabolism Female Homeostasis Humanities and Social Sciences Insects Internalization Juvenile Hormones - physiology Lipids Localization Mechanoreceptors - physiology Microfilament Proteins - metabolism multidisciplinary Multidisciplinary Sciences Organogenesis - drug effects Organogenesis - genetics Phenotypes Phosphatidic acid Phosphatidic Acids - pharmacology Phospholipase D Protein transport Protein Transport - genetics Receptors, Notch - metabolism Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Sense organs Signal transduction Signal Transduction - drug effects
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