Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection
•Water-soluble fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed.•The sensing mechanism of probe with HOCl was elucidated.•The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively.•The probe PTZ-MP was further used for t...
Gespeichert in:
| Veröffentlicht in: | Journal of molecular structure 2021-03, Vol.1227, p.129523, Article 129523 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 129523 |
| container_title | Journal of molecular structure |
| container_volume | 1227 |
| creator | Liang, Lijuan Sun, Yimeng Liu, Chang Jiao, Xiaojie Shang, Ye Zeng, Xianshun Zhao, Liancheng Zhao, Jianlong |
| description | •Water-soluble fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed.•The sensing mechanism of probe with HOCl was elucidated.•The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively.•The probe PTZ-MP was further used for the detection of viscosity.
Due to the important role of hypochlorous acid (HOCl) in immune prevention of bacteria towards living organisms and its variations may be related to the change of intracellular viscosity, it is significant to design fluorescent probe to accurately analyze changes for detecting HOCl and viscosity simultaneously. In this paper, water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of the probe with HOCl was elucidated by emission spectra at long and short excited wavelength 480 and 380 nm, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, the probe PTZ-MP was further used for the detection of viscosity. Furthermore, cell imaging of PTZ-TPP towards HOCl was conducted. And it is expected to be used in simultaneous determination of HOCl and viscosity in intracellular.
A novel water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of probe with HOCl was elucidated by emission spectra at different excited wavelength, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, probe PTZ-MP was further used for the detection of viscosity, and PTZ-TPP can be employed for specific detection of NaClO in living INS-1 cells. [Display omitted] |
| doi_str_mv | 10.1016/j.molstruc.2020.129523 |
| format | Article |
| fullrecord | <record><control><sourceid>elsevier_webof</sourceid><recordid>TN_cdi_webofscience_primary_000609153800018CitationCount</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S002228602031838X</els_id><sourcerecordid>S002228602031838X</sourcerecordid><originalsourceid>FETCH-LOGICAL-c312t-a4e6b8d7f5602e4a2deceb1ad41c834602493b694ea8772ba90807b54e3534fa3</originalsourceid><addsrcrecordid>eNqN0EFLwzAUwPEgCs7pV5DcpTNJ0za9KUWdIHhQzyFNX11G14wknfTbm9LpVU-Bx_s_wg-ha0pWlND8drva2c4HN-gVIywOWZmx9AQtqChYIgjlp2hBCGMJEzk5RxfebwkhNMYL9LY2n5tuxB460MEcAIfB9YntcdsN1oHX0Ae8d7YG3FqHN-Pe6k1nnQmAVd_gg_HaehNG3ECYTtj-Ep21qvNwdXyX6OPx4b1aJy-vT8_V_UuiU8pCojjktWiKNssJA65YAxpqqhpOtUh5HPIyrfOSgxJFwWpVEkGKOuOQZilvVbpE-XxXO-u9g1bundkpN0pK5EQjt_KHRk40cqaJ4c0cfkFtW68N9Bp-42iTk5JmqZiURNwW_9-uTFCTQWWHPsT0bk4hMhwMOHnMG-OilWys-euv3wZDkz4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection</title><source>Access via ScienceDirect (Elsevier)</source><creator>Liang, Lijuan ; Sun, Yimeng ; Liu, Chang ; Jiao, Xiaojie ; Shang, Ye ; Zeng, Xianshun ; Zhao, Liancheng ; Zhao, Jianlong</creator><creatorcontrib>Liang, Lijuan ; Sun, Yimeng ; Liu, Chang ; Jiao, Xiaojie ; Shang, Ye ; Zeng, Xianshun ; Zhao, Liancheng ; Zhao, Jianlong</creatorcontrib><description>•Water-soluble fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed.•The sensing mechanism of probe with HOCl was elucidated.•The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively.•The probe PTZ-MP was further used for the detection of viscosity.
Due to the important role of hypochlorous acid (HOCl) in immune prevention of bacteria towards living organisms and its variations may be related to the change of intracellular viscosity, it is significant to design fluorescent probe to accurately analyze changes for detecting HOCl and viscosity simultaneously. In this paper, water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of the probe with HOCl was elucidated by emission spectra at long and short excited wavelength 480 and 380 nm, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, the probe PTZ-MP was further used for the detection of viscosity. Furthermore, cell imaging of PTZ-TPP towards HOCl was conducted. And it is expected to be used in simultaneous determination of HOCl and viscosity in intracellular.
A novel water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of probe with HOCl was elucidated by emission spectra at different excited wavelength, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, probe PTZ-MP was further used for the detection of viscosity, and PTZ-TPP can be employed for specific detection of NaClO in living INS-1 cells. [Display omitted]</description><identifier>ISSN: 0022-2860</identifier><identifier>EISSN: 1872-8014</identifier><identifier>DOI: 10.1016/j.molstruc.2020.129523</identifier><language>eng</language><publisher>AMSTERDAM: Elsevier B.V</publisher><subject>Chemistry ; Chemistry, Physical ; Fluorescence ; Hypochlorite ; Phenothiazine ; Physical Sciences ; Science & Technology ; Viscosity</subject><ispartof>Journal of molecular structure, 2021-03, Vol.1227, p.129523, Article 129523</ispartof><rights>2020 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>19</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000609153800018</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c312t-a4e6b8d7f5602e4a2deceb1ad41c834602493b694ea8772ba90807b54e3534fa3</citedby><cites>FETCH-LOGICAL-c312t-a4e6b8d7f5602e4a2deceb1ad41c834602493b694ea8772ba90807b54e3534fa3</cites><orcidid>0000-0002-1255-2764</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.molstruc.2020.129523$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27928,27929,45999</link.rule.ids></links><search><creatorcontrib>Liang, Lijuan</creatorcontrib><creatorcontrib>Sun, Yimeng</creatorcontrib><creatorcontrib>Liu, Chang</creatorcontrib><creatorcontrib>Jiao, Xiaojie</creatorcontrib><creatorcontrib>Shang, Ye</creatorcontrib><creatorcontrib>Zeng, Xianshun</creatorcontrib><creatorcontrib>Zhao, Liancheng</creatorcontrib><creatorcontrib>Zhao, Jianlong</creatorcontrib><title>Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection</title><title>Journal of molecular structure</title><addtitle>J MOL STRUCT</addtitle><description>•Water-soluble fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed.•The sensing mechanism of probe with HOCl was elucidated.•The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively.•The probe PTZ-MP was further used for the detection of viscosity.
Due to the important role of hypochlorous acid (HOCl) in immune prevention of bacteria towards living organisms and its variations may be related to the change of intracellular viscosity, it is significant to design fluorescent probe to accurately analyze changes for detecting HOCl and viscosity simultaneously. In this paper, water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of the probe with HOCl was elucidated by emission spectra at long and short excited wavelength 480 and 380 nm, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, the probe PTZ-MP was further used for the detection of viscosity. Furthermore, cell imaging of PTZ-TPP towards HOCl was conducted. And it is expected to be used in simultaneous determination of HOCl and viscosity in intracellular.
A novel water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of probe with HOCl was elucidated by emission spectra at different excited wavelength, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, probe PTZ-MP was further used for the detection of viscosity, and PTZ-TPP can be employed for specific detection of NaClO in living INS-1 cells. [Display omitted]</description><subject>Chemistry</subject><subject>Chemistry, Physical</subject><subject>Fluorescence</subject><subject>Hypochlorite</subject><subject>Phenothiazine</subject><subject>Physical Sciences</subject><subject>Science & Technology</subject><subject>Viscosity</subject><issn>0022-2860</issn><issn>1872-8014</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><recordid>eNqN0EFLwzAUwPEgCs7pV5DcpTNJ0za9KUWdIHhQzyFNX11G14wknfTbm9LpVU-Bx_s_wg-ha0pWlND8drva2c4HN-gVIywOWZmx9AQtqChYIgjlp2hBCGMJEzk5RxfebwkhNMYL9LY2n5tuxB460MEcAIfB9YntcdsN1oHX0Ae8d7YG3FqHN-Pe6k1nnQmAVd_gg_HaehNG3ECYTtj-Ep21qvNwdXyX6OPx4b1aJy-vT8_V_UuiU8pCojjktWiKNssJA65YAxpqqhpOtUh5HPIyrfOSgxJFwWpVEkGKOuOQZilvVbpE-XxXO-u9g1bundkpN0pK5EQjt_KHRk40cqaJ4c0cfkFtW68N9Bp-42iTk5JmqZiURNwW_9-uTFCTQWWHPsT0bk4hMhwMOHnMG-OilWys-euv3wZDkz4</recordid><startdate>20210305</startdate><enddate>20210305</enddate><creator>Liang, Lijuan</creator><creator>Sun, Yimeng</creator><creator>Liu, Chang</creator><creator>Jiao, Xiaojie</creator><creator>Shang, Ye</creator><creator>Zeng, Xianshun</creator><creator>Zhao, Liancheng</creator><creator>Zhao, Jianlong</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-1255-2764</orcidid></search><sort><creationdate>20210305</creationdate><title>Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection</title><author>Liang, Lijuan ; Sun, Yimeng ; Liu, Chang ; Jiao, Xiaojie ; Shang, Ye ; Zeng, Xianshun ; Zhao, Liancheng ; Zhao, Jianlong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c312t-a4e6b8d7f5602e4a2deceb1ad41c834602493b694ea8772ba90807b54e3534fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Chemistry</topic><topic>Chemistry, Physical</topic><topic>Fluorescence</topic><topic>Hypochlorite</topic><topic>Phenothiazine</topic><topic>Physical Sciences</topic><topic>Science & Technology</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liang, Lijuan</creatorcontrib><creatorcontrib>Sun, Yimeng</creatorcontrib><creatorcontrib>Liu, Chang</creatorcontrib><creatorcontrib>Jiao, Xiaojie</creatorcontrib><creatorcontrib>Shang, Ye</creatorcontrib><creatorcontrib>Zeng, Xianshun</creatorcontrib><creatorcontrib>Zhao, Liancheng</creatorcontrib><creatorcontrib>Zhao, Jianlong</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>CrossRef</collection><jtitle>Journal of molecular structure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liang, Lijuan</au><au>Sun, Yimeng</au><au>Liu, Chang</au><au>Jiao, Xiaojie</au><au>Shang, Ye</au><au>Zeng, Xianshun</au><au>Zhao, Liancheng</au><au>Zhao, Jianlong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection</atitle><jtitle>Journal of molecular structure</jtitle><stitle>J MOL STRUCT</stitle><date>2021-03-05</date><risdate>2021</risdate><volume>1227</volume><spage>129523</spage><pages>129523-</pages><artnum>129523</artnum><issn>0022-2860</issn><eissn>1872-8014</eissn><abstract>•Water-soluble fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed.•The sensing mechanism of probe with HOCl was elucidated.•The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively.•The probe PTZ-MP was further used for the detection of viscosity.
Due to the important role of hypochlorous acid (HOCl) in immune prevention of bacteria towards living organisms and its variations may be related to the change of intracellular viscosity, it is significant to design fluorescent probe to accurately analyze changes for detecting HOCl and viscosity simultaneously. In this paper, water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of the probe with HOCl was elucidated by emission spectra at long and short excited wavelength 480 and 380 nm, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, the probe PTZ-MP was further used for the detection of viscosity. Furthermore, cell imaging of PTZ-TPP towards HOCl was conducted. And it is expected to be used in simultaneous determination of HOCl and viscosity in intracellular.
A novel water-soluble, very fast-responsive fluorescent probes PTZ-TPP and PTZ-MP based on phenothiazine moiety were developed. The sensing mechanism of probe with HOCl was elucidated by emission spectra at different excited wavelength, and the oxidation structure OPTZ-TPP, sulfur peroxide structure O3PTZ-TPP as well as carbon-carbon double bond cleavage structure OCy-TPP were confirmed by ESI-MS analysis. The detection limit (LOD) of probe PTZ-TPP and PTZ-MP was evaluated to be 14.7 and 19.4 nM respectively. Moreover, probe PTZ-MP was further used for the detection of viscosity, and PTZ-TPP can be employed for specific detection of NaClO in living INS-1 cells. [Display omitted]</abstract><cop>AMSTERDAM</cop><pub>Elsevier B.V</pub><doi>10.1016/j.molstruc.2020.129523</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1255-2764</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-2860 |
| ispartof | Journal of molecular structure, 2021-03, Vol.1227, p.129523, Article 129523 |
| issn | 0022-2860 1872-8014 |
| language | eng |
| recordid | cdi_webofscience_primary_000609153800018CitationCount |
| source | Access via ScienceDirect (Elsevier) |
| subjects | Chemistry Chemistry, Physical Fluorescence Hypochlorite Phenothiazine Physical Sciences Science & Technology Viscosity |
| title | Highly selective turn-on fluorescent probe for hypochlorite and viscosity detection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T23%3A42%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-elsevier_webof&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Highly%20selective%20turn-on%20fluorescent%20probe%20for%20hypochlorite%20and%20viscosity%20detection&rft.jtitle=Journal%20of%20molecular%20structure&rft.au=Liang,%20Lijuan&rft.date=2021-03-05&rft.volume=1227&rft.spage=129523&rft.pages=129523-&rft.artnum=129523&rft.issn=0022-2860&rft.eissn=1872-8014&rft_id=info:doi/10.1016/j.molstruc.2020.129523&rft_dat=%3Celsevier_webof%3ES002228602031838X%3C/elsevier_webof%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_els_id=S002228602031838X&rfr_iscdi=true |