The Intellicage system provides a reproducible and standardized method to assess behavioral changes in cuprizone-induced demyelination mouse model

•Cuprizone intoxication triggers demyelination as well as underlying behavioural deficits.•Classical behavioral analyses are not sensitive enough to detect behavioral changes consistently.•Automated Intellicage system shows reproducible motor deficits in cuprizone-intoxicated mice. Multiple sclerosi...

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Veröffentlicht in:	Behavioural brain research 2021-02, Vol.400, p.113039-113039, Article 113039
Hauptverfasser:	Cisbani, Giulia, Poggini, Silvia, Laflamme, Nataly, Pons, Vincent, Tremblay, Marie-Ève, Branchi, Igor, Rivest, Serge
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavioral Sciences Behaviour Cuprizone intoxication Demyelination Intellicage Life Sciences & Biomedicine Multiple sclerosis Neurosciences Neurosciences & Neurology Science & Technology
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