Correction of CFTR function in intestinal organoids to guide treatment of cystic fibrosis

Rationale: Given the vast number of cystic fibrosis transmembrane conductance regulator (CFTR) mutations, biomarkers predicting benefit from CFTR modulator therapies are needed for subjects with cystic fibrosis (CF). Objectives: To study CFTR function in organoids of subjects with common and rare CF...

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Veröffentlicht in:	The European respiratory journal 2021-01, Vol.57 (1), p.1902426, Article 1902426
Hauptverfasser:	Ramalho, Anabela S., Fuerstova, Eva, Vonk, Annelotte M., Ferrante, Marc, Verfaillie, Catherine, Dupont, Lieven, Boon, Mieke, Proesmans, Marijke, Beekman, Jeffrey M., Sarouk, Ifat, Vazquez Cordero, Carlos, Vermeulen, Francois, De Boeck, Kris
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences & Biomedicine Respiratory System Science & Technology
Online-Zugang:	Volltext
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