Directly Compressed Tablets: A Novel Drug‐Containing Reservoir Combined with Hydrogel‐Forming Microneedle Arrays for Transdermal Drug Delivery

Microneedle (MN) patches consist of a hydrogel‐forming MN array and a drug‐containing reservoir. Drug‐containing reservoirs documented in the literature include polymeric films and lyophilized wafers. While effective, both reservoir formulations are aqueous based, and so degradation can occur during...

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Veröffentlicht in:	Advanced healthcare materials 2021-02, Vol.10 (3), p.e2001256-n/a, Article 2001256
Hauptverfasser:	McAlister, Emma, Dutton, Bridie, Vora, Lalitkumar K., Zhao, Li, Ripolin, Anastasia, Zahari, Dk Siti Zawanah Binti Pg Hj, Quinn, Helen L., Tekko, Ismaiel A., Courtenay, Aaron J., Kelly, Stephen A., Rodgers, Aoife M., Steiner, Lilach, Levin, Galit, Levy‐Nissenbaum, Etgar, Shterman, Nava, McCarthy, Helen O., Donnelly, Ryan F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Amoxicillin Animals Aqueous solutions Arrays Chemical precipitation directly compressed tablets Drug delivery Drug Delivery Systems drug‐containing reservoirs Drying Engineering Engineering, Biomedical Hydrogels hydrogel‐forming microneedle arrays In vivo methods and tests in vivo pharmacokinetic studies Levodopa Levofloxacin Materials Science Materials Science, Biomaterials Microinjections Nanoscience & Nanotechnology Needles Patches (structures) Pharmacokinetics Polymer films Polyvinyl alcohol Primaquine Rats Reservoirs Science & Technology Science & Technology - Other Topics Skin Tablets Technology transdermal drug delivery Transdermal medication
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