The effect of nanoparticle presence on aerosol formation during nanoparticle-enhanced laser ablation inductively coupled plasma mass spectrometry

The changes in aerosol physical properties were studied by applying Nanoparticle-Enhanced Laser Ablation Inductively Coupled Plasma Mass Spectrometry (NE-LA-ICP-MS). This approach was compared to conventional LA-ICP-MS method. Analyte signal enhancement was related to the particle number concentration of aerosol for three sizes of Au nanoparticles (NPs) applied on the metal sample surface in the form of droplets. The dependence of the number of generated particles on the laser fluence in the range from 0.5 to 10 J cm −2 was studied. A different shape of the particle size distribution (PSD) of NE-LA-ICP-MS and LA-ICP-MS aerosol was determined. The aerosol structure was additionally studied on filters using scanning electron microscopy (SEM). Compared to LA-ICP-MS, NE-LA-ICP-MS produced a larger proportion of small particles (