Changes in mercury distribution and its body burden in delphinids affected by a morbillivirus infection: Evidences of methylmercury intoxication in Guiana dolphin
An unusual mortality event (UME) attributed to morbillivirus infection was identified in two Guiana dolphin populations from the Southeastern Brazilian coast. The aim of this study was to characterize total mercury (THg), methylmercury (MeHg) and selenium (Se) bioaccumulation and body burden in Guia...
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| Veröffentlicht in: | Chemosphere (Oxford) 2021-01, Vol.263, p.128286, Article 128286 |
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| creator | Manhães, B.M.R. Santos-Neto, E.B. Tovar, L.R. Guari, E.B. Flach, L. Kasper, D. Galvão, P.M.A. Malm, O. Gonçalves, R.A. Bisi, T.L. Azevedo, A.F. Lailson-Brito, J. |
| description | An unusual mortality event (UME) attributed to morbillivirus infection was identified in two Guiana dolphin populations from the Southeastern Brazilian coast. The aim of this study was to characterize total mercury (THg), methylmercury (MeHg) and selenium (Se) bioaccumulation and body burden in Guiana dolphins from Sepetiba Bay (RJ) collected before (n = 61) and during the UME (n = 20). Significantly lower Se concentrations were found in the livers of individuals collected during the UME (Mann-Whitney test; p = 0.03), probably due to impairment of the detoxification process in the liver. There were differences in THg and Se concentrations in the organs and tissues of individuals (Kruskal-Wallis test, p |
| doi_str_mv | 10.1016/j.chemosphere.2020.128286 |
| format | Article |
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[Display omitted]
•Guiana dolphins from the UME showed signs of impaired detoxification of MeHg.•A high methyl mercury dose was remobilized from Guiana dolphins’ muscle in the UME.•Selenium was remobilized from the skin to organs with higher MeHg concentrations.•Body burden profiles changed in Guiana dolphins with morbillivirus infection.•Methyl mercury can act as another pressure in Guiana dolphins’ immunologic system.</description><identifier>ISSN: 0045-6535</identifier><identifier>EISSN: 1879-1298</identifier><identifier>DOI: 10.1016/j.chemosphere.2020.128286</identifier><identifier>PMID: 33297230</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Bioaccumulation ; Body Burden ; Brazil ; Cetaceans ; Dolphins ; Emerging disease ; Environmental Monitoring ; Humans ; Mercury - analysis ; Methylmercury Compounds - analysis ; Methylmercury Compounds - toxicity ; Morbillivirus ; Poor body condition ; Remobilization ; Selenium - analysis ; Trace elements ; Water Pollutants, Chemical - analysis ; Water Pollutants, Chemical - toxicity</subject><ispartof>Chemosphere (Oxford), 2021-01, Vol.263, p.128286, Article 128286</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c377t-6f7bfa1a670720da9d8f522cc29f89d44b1475a6814be21005ca5bedea6aa72a3</citedby><cites>FETCH-LOGICAL-c377t-6f7bfa1a670720da9d8f522cc29f89d44b1475a6814be21005ca5bedea6aa72a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chemosphere.2020.128286$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33297230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Manhães, B.M.R.</creatorcontrib><creatorcontrib>Santos-Neto, E.B.</creatorcontrib><creatorcontrib>Tovar, L.R.</creatorcontrib><creatorcontrib>Guari, E.B.</creatorcontrib><creatorcontrib>Flach, L.</creatorcontrib><creatorcontrib>Kasper, D.</creatorcontrib><creatorcontrib>Galvão, P.M.A.</creatorcontrib><creatorcontrib>Malm, O.</creatorcontrib><creatorcontrib>Gonçalves, R.A.</creatorcontrib><creatorcontrib>Bisi, T.L.</creatorcontrib><creatorcontrib>Azevedo, A.F.</creatorcontrib><creatorcontrib>Lailson-Brito, J.</creatorcontrib><title>Changes in mercury distribution and its body burden in delphinids affected by a morbillivirus infection: Evidences of methylmercury intoxication in Guiana dolphin</title><title>Chemosphere (Oxford)</title><addtitle>Chemosphere</addtitle><description>An unusual mortality event (UME) attributed to morbillivirus infection was identified in two Guiana dolphin populations from the Southeastern Brazilian coast. The aim of this study was to characterize total mercury (THg), methylmercury (MeHg) and selenium (Se) bioaccumulation and body burden in Guiana dolphins from Sepetiba Bay (RJ) collected before (n = 61) and during the UME (n = 20). Significantly lower Se concentrations were found in the livers of individuals collected during the UME (Mann-Whitney test; p = 0.03), probably due to impairment of the detoxification process in the liver. There were differences in THg and Se concentrations in the organs and tissues of individuals (Kruskal-Wallis test, p < 0.05), but not MeHg (Kruskal-Wallis test, p = 0.07). For THg, the liver showed the higher concentrations and differed among organs and tissues analyzed such as blubber (Tukey’s test for unequal N; p = 0.003). For Se concentrations, the skin and kidney presented the higher concentrations and varied among other tissues/organs, like muscle (Tukey’s test for unequal N; p = 0.02). Differences in body burdens were observed among specimens collected previously and during the UME probably due to the remobilization and transport of the muscle-stored MeHg to other tissues/organs. This abrupt input of MeHg into the bloodstream may cause serious health damage. Indeed, evidences of methylmercury intoxication was observed in Guiana dolphins in Sepetiba Bay. In conclusion, bioaccumulation patterns, the detoxification process and body burden were affected by morbillivirus.
[Display omitted]
•Guiana dolphins from the UME showed signs of impaired detoxification of MeHg.•A high methyl mercury dose was remobilized from Guiana dolphins’ muscle in the UME.•Selenium was remobilized from the skin to organs with higher MeHg concentrations.•Body burden profiles changed in Guiana dolphins with morbillivirus infection.•Methyl mercury can act as another pressure in Guiana dolphins’ immunologic system.</description><subject>Animals</subject><subject>Bioaccumulation</subject><subject>Body Burden</subject><subject>Brazil</subject><subject>Cetaceans</subject><subject>Dolphins</subject><subject>Emerging disease</subject><subject>Environmental Monitoring</subject><subject>Humans</subject><subject>Mercury - analysis</subject><subject>Methylmercury Compounds - analysis</subject><subject>Methylmercury Compounds - toxicity</subject><subject>Morbillivirus</subject><subject>Poor body condition</subject><subject>Remobilization</subject><subject>Selenium - analysis</subject><subject>Trace elements</subject><subject>Water Pollutants, Chemical - analysis</subject><subject>Water Pollutants, Chemical - toxicity</subject><issn>0045-6535</issn><issn>1879-1298</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkM1u1DAUhS0EokPpKyDzABls58cJOzQqbaVKbGBtXf81d5TEIzsZkdfhSXE6FLFkZck-53zyR8hHzvac8ebTcW96N4Z06l10e8FEvhetaJtXZMdb2RVcdO1rsmOsqoumLusr8i6lI2O5XHdvyVVZik6Kku3Ir0MP05NLFCc6umiWuFKLaY6olxnDRGGyFOdEdbAr1Uu0btqy1g2nHie0iYL3zszOUr1SoGOIGocBzxiXbXV7yzuf6e0Zc9dkVPAZNffr8ALEaQ4_0cAzMI_fLQgTUBueGe_JGw9Dcjd_zmvy4-vt98N98fjt7uHw5bEwpZRz0XipPXBoJJOCWehs62shjBGdbztbVZpXsoam5ZV2gjNWG6i1sw4aACmgvCbdZdfEkFJ0Xp0ijhBXxZnavKuj-se72ryri_fc_XDpnhY9Ovu3-SI6Bw6XgMs_OKOLKhncdFiM2ZCyAf8D8xv71J-a</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Manhães, B.M.R.</creator><creator>Santos-Neto, E.B.</creator><creator>Tovar, L.R.</creator><creator>Guari, E.B.</creator><creator>Flach, L.</creator><creator>Kasper, D.</creator><creator>Galvão, P.M.A.</creator><creator>Malm, O.</creator><creator>Gonçalves, R.A.</creator><creator>Bisi, T.L.</creator><creator>Azevedo, A.F.</creator><creator>Lailson-Brito, J.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>202101</creationdate><title>Changes in mercury distribution and its body burden in delphinids affected by a morbillivirus infection: Evidences of methylmercury intoxication in Guiana dolphin</title><author>Manhães, B.M.R. ; Santos-Neto, E.B. ; Tovar, L.R. ; Guari, E.B. ; Flach, L. ; Kasper, D. ; Galvão, P.M.A. ; Malm, O. ; Gonçalves, R.A. ; Bisi, T.L. ; Azevedo, A.F. ; Lailson-Brito, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-6f7bfa1a670720da9d8f522cc29f89d44b1475a6814be21005ca5bedea6aa72a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Animals</topic><topic>Bioaccumulation</topic><topic>Body Burden</topic><topic>Brazil</topic><topic>Cetaceans</topic><topic>Dolphins</topic><topic>Emerging disease</topic><topic>Environmental Monitoring</topic><topic>Humans</topic><topic>Mercury - analysis</topic><topic>Methylmercury Compounds - analysis</topic><topic>Methylmercury Compounds - toxicity</topic><topic>Morbillivirus</topic><topic>Poor body condition</topic><topic>Remobilization</topic><topic>Selenium - analysis</topic><topic>Trace elements</topic><topic>Water Pollutants, Chemical - analysis</topic><topic>Water Pollutants, Chemical - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manhães, B.M.R.</creatorcontrib><creatorcontrib>Santos-Neto, E.B.</creatorcontrib><creatorcontrib>Tovar, L.R.</creatorcontrib><creatorcontrib>Guari, E.B.</creatorcontrib><creatorcontrib>Flach, L.</creatorcontrib><creatorcontrib>Kasper, D.</creatorcontrib><creatorcontrib>Galvão, P.M.A.</creatorcontrib><creatorcontrib>Malm, O.</creatorcontrib><creatorcontrib>Gonçalves, R.A.</creatorcontrib><creatorcontrib>Bisi, T.L.</creatorcontrib><creatorcontrib>Azevedo, A.F.</creatorcontrib><creatorcontrib>Lailson-Brito, J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Chemosphere (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manhães, B.M.R.</au><au>Santos-Neto, E.B.</au><au>Tovar, L.R.</au><au>Guari, E.B.</au><au>Flach, L.</au><au>Kasper, D.</au><au>Galvão, P.M.A.</au><au>Malm, O.</au><au>Gonçalves, R.A.</au><au>Bisi, T.L.</au><au>Azevedo, A.F.</au><au>Lailson-Brito, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes in mercury distribution and its body burden in delphinids affected by a morbillivirus infection: Evidences of methylmercury intoxication in Guiana dolphin</atitle><jtitle>Chemosphere (Oxford)</jtitle><addtitle>Chemosphere</addtitle><date>2021-01</date><risdate>2021</risdate><volume>263</volume><spage>128286</spage><pages>128286-</pages><artnum>128286</artnum><issn>0045-6535</issn><eissn>1879-1298</eissn><abstract>An unusual mortality event (UME) attributed to morbillivirus infection was identified in two Guiana dolphin populations from the Southeastern Brazilian coast. The aim of this study was to characterize total mercury (THg), methylmercury (MeHg) and selenium (Se) bioaccumulation and body burden in Guiana dolphins from Sepetiba Bay (RJ) collected before (n = 61) and during the UME (n = 20). Significantly lower Se concentrations were found in the livers of individuals collected during the UME (Mann-Whitney test; p = 0.03), probably due to impairment of the detoxification process in the liver. There were differences in THg and Se concentrations in the organs and tissues of individuals (Kruskal-Wallis test, p < 0.05), but not MeHg (Kruskal-Wallis test, p = 0.07). For THg, the liver showed the higher concentrations and differed among organs and tissues analyzed such as blubber (Tukey’s test for unequal N; p = 0.003). For Se concentrations, the skin and kidney presented the higher concentrations and varied among other tissues/organs, like muscle (Tukey’s test for unequal N; p = 0.02). Differences in body burdens were observed among specimens collected previously and during the UME probably due to the remobilization and transport of the muscle-stored MeHg to other tissues/organs. This abrupt input of MeHg into the bloodstream may cause serious health damage. Indeed, evidences of methylmercury intoxication was observed in Guiana dolphins in Sepetiba Bay. In conclusion, bioaccumulation patterns, the detoxification process and body burden were affected by morbillivirus.
[Display omitted]
•Guiana dolphins from the UME showed signs of impaired detoxification of MeHg.•A high methyl mercury dose was remobilized from Guiana dolphins’ muscle in the UME.•Selenium was remobilized from the skin to organs with higher MeHg concentrations.•Body burden profiles changed in Guiana dolphins with morbillivirus infection.•Methyl mercury can act as another pressure in Guiana dolphins’ immunologic system.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>33297230</pmid><doi>10.1016/j.chemosphere.2020.128286</doi></addata></record> |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Bioaccumulation Body Burden Brazil Cetaceans Dolphins Emerging disease Environmental Monitoring Humans Mercury - analysis Methylmercury Compounds - analysis Methylmercury Compounds - toxicity Morbillivirus Poor body condition Remobilization Selenium - analysis Trace elements Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity |
| title | Changes in mercury distribution and its body burden in delphinids affected by a morbillivirus infection: Evidences of methylmercury intoxication in Guiana dolphin |
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