Discovery of a cobalt (III) salen complex that induces apoptosis in Burkitt like lymphoma and leukemia cells, overcoming multidrug resistance in vitro

[Display omitted] •A cobalt-salen complex, named MBR-60, showed apoptotic activity over the intrinsic pathway in leukemia and lymphoma cells.•The cobalt-free ligand did not affect tumor cells.•MBR-60 overcame multidrug resistances.•Outstanding synergistic effects of MBR-60 with daunorubicin and vinc...

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