Predictive factors of Boston Type I Keratoprosthesis outcomes: A long-term analysis

To study the long-term visual- and device retention-related outcomes and complications of the Boston Type I Keratoprosthesis (KPro). Single-center, retrospective cohort study of all patients undergoing KPro implantation from February 2007 to April 2014 with at least 5 years of follow-up. 68 eyes from 65 patients underwent KPro implantation during the study period. At 5 and 10 years, the probability of maintaining or improving visual acuity (VA) was 75.0% and 66.7%, respectively, and the probability of KPro retention was 89.2% and 89.2%, respectively. Initial device retention rate at 10 years was significantly lower in those with underlying ocular surface disease (46.8% [30.6–63.2] vs 75.8% [61.0–90.7], P = 0.03), while other baseline characteristics showed no significant association. Final VA was more likely to be stable or improved in patients with fewer failed grafts (2 [1–6] vs 3 [1–6], P