Hyperammonemia with impaired consciousness caused by continuous 5-fluorouracil infusion for colorectal cancer: A case report

A 66-year-old woman was diagnosed with stage IVb sigmoid colon cancer. Modified FOLFOX-6 (mFOLFOX-6; levofolinate-fluorouracil-oxaliplafin) plus panitumumab was selected as the chemotherapeutic regimen, but she was administered a regimen without oxaliplatin (L-OHP) or bolus 5-fluorouracil (5-FU) bec...

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Veröffentlicht in:	International journal of clinical pharmacology and therapeutics 2020-12, Vol.58 (12), p.727-731
Hauptverfasser:	Nakamura, Toshiki, Shibata, Soichi, Miyatani, Yusuke, Matsubara, Hajime
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amino acids Antineoplastic Combined Chemotherapy Protocols - adverse effects Blood Cancer therapies Case reports Chemotherapy Colorectal cancer Colorectal Neoplasms - drug therapy Consciousness Drug dosages Female Fluorouracil - adverse effects Humans Hyperammonemia - chemically induced Hyperammonemia - drug therapy Intestinal obstruction Laboratories Leucovorin - adverse effects Life Sciences & Biomedicine Magnetic resonance imaging Metastasis Pharmacology & Pharmacy Pharmacy Science & Technology Surgery
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