Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4(+) T cell counts 350 cells/mm(3) - A potential hallmark of chronic inflammation

Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4(+) T cell counts 350 cells/mm(3) - A potential hallmark of chronic inflammation

The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1 beta, IL-8, and IL-12p70) of HIV+ individuals w...

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Veröffentlicht in:Microbes and infection 2020-10, Vol.22 (9), p.474-480
Hauptverfasser: Ellwanger, Joel Henrique, Valverde-Villegas, Jacqueline Maria, Kaminski, Valeria de Lima, de Medeiros, Rubia Marilia, de Matos Almeida, Sabrina Esteves, Santos, Breno Riegel, de Melo, Marineide Goncalves, Hackenhaar, Fernanda Schafer, Bogo Chies, Jose Artur
Format: Artikel
Sprache:eng
Schlagworte:
Immunology
Infectious Diseases
Life Sciences & Biomedicine
Microbiology
Science & Technology
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Zusammenfassung:The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1 beta, IL-8, and IL-12p70) of HIV+ individuals who initiated ART after immunosuppression (CD4(+) T cell counts
ISSN:1286-4579
1769-714X
DOI:10.1016/j.micinf.2020.05.019