Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer's Disease

Glial gap junction proteins, called connexins (Cxs), form gap junctions in the central nervous system (CNS) to allow the bidirectional cytosolic exchange of molecules between adjacent cells. Their involvement in inheritable diseases and the use of experimental animal models that closely mimic such d...

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Veröffentlicht in:	Frontiers in neuroscience 2020-10, Vol.14, p.582934-582934
Hauptverfasser:	Angeli, Stella, Kousiappa, Ioanna, Stavrou, Marios, Sargiannidou, Irene, Georgiou, Elena, Papacostas, Savvas S, Kleopa, Kleopas A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animal cognition Animal models Central nervous system Connexin 43 Connexins Cx30 Cx43 Cx47 Demyelination Disease Gap junctions Gene expression Glial stem cells Gliosis Homeostasis Immunoreactivity Multiple sclerosis Mutation Myelination Nervous system Neural networks Neurodegeneration Neurodegenerative diseases Neuroscience Peptides Plaques Proteins Rodents Thalamus Toxicity Transgenic animals
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