Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria
Lactic acid bacteria (LAB) have a long historical record of usage in many types of food-related bioprocesses, and as LAB have been found to have intrinsic beneficial effects on human health, interest in using LAB as a medical treatment has increased. Moreover, recent advances in synthetic biology ha...
Gespeichert in:
| Veröffentlicht in: | Biotechnology and bioprocess engineering 2020, 25(6), , pp.962-973 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 973 |
|---|---|
| container_issue | 6 |
| container_start_page | 962 |
| container_title | Biotechnology and bioprocess engineering |
| container_volume | 25 |
| creator | Son, Jaewoo Jeong, Ki Jun |
| description | Lactic acid bacteria (LAB) have a long historical record of usage in many types of food-related bioprocesses, and as LAB have been found to have intrinsic beneficial effects on human health, interest in using LAB as a medical treatment has increased. Moreover, recent advances in synthetic biology have enabled the engineering of so-called “smart” bacteria with the native characteristics of LAB. With various synthetic parts for gene expression, genome editing, and genetic circuits, gene expression can be precisely regulated in LAB. Moreover, LAB have been successfully developed as potential hosts for therapeutics to detect and control specific diseases or to deliver drug molecules. In this review, we outline the recent development of synthetic parts and approaches for the engineering of LAB. We also discuss the potential application of synthetic biology for the utilization of LAB as living therapeutics. |
| doi_str_mv | 10.1007/s12257-020-0033-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_nrf_k</sourceid><recordid>TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_9670871</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2476049342</sourcerecordid><originalsourceid>FETCH-LOGICAL-c350t-f2dacd286a82218b9151d0b9ebe529b7670d826945b8819a694b7e46337afe523</originalsourceid><addsrcrecordid>eNp1kM1KAzEUhYMoWKsP4C7gysVofmaSzLItVQsFpdZ1yGQyY9qa1GQq9O3NOIIrV_dw7zmHywfANUZ3GCF-HzEhBc8QQRlClGbsBIxwyVlGBWanSRPCMkE5OQcXMW4QyrkQYgReVkYb18FJ_aWcNhFaB1-Prns3ndVwav3Ot0fY-ADTCs5da50xwboW-gYule5dE21rOE06HdQlOGvULpqr3zkGbw_z9ewpWz4_LmaTZaZpgbqsIbXSNRFMCUKwqEpc4BpVpalMQcqKM45qQViZF5UQuFRJVdzkjFKummShY3A79LrQyK220iv7M1svt0FOVuuFLFOL4Dh5bwbvPvjPg4md3PhDcOk9SXLOUF7SvG_Eg0sHH2MwjdwH-6HCUWIke8hygCwTZNlDlixlyJCJ-x6KCX_N_4e-ATFvfJk</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2476049342</pqid></control><display><type>article</type><title>Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria</title><source>SpringerLink Journals - AutoHoldings</source><creator>Son, Jaewoo ; Jeong, Ki Jun</creator><creatorcontrib>Son, Jaewoo ; Jeong, Ki Jun</creatorcontrib><description>Lactic acid bacteria (LAB) have a long historical record of usage in many types of food-related bioprocesses, and as LAB have been found to have intrinsic beneficial effects on human health, interest in using LAB as a medical treatment has increased. Moreover, recent advances in synthetic biology have enabled the engineering of so-called “smart” bacteria with the native characteristics of LAB. With various synthetic parts for gene expression, genome editing, and genetic circuits, gene expression can be precisely regulated in LAB. Moreover, LAB have been successfully developed as potential hosts for therapeutics to detect and control specific diseases or to deliver drug molecules. In this review, we outline the recent development of synthetic parts and approaches for the engineering of LAB. We also discuss the potential application of synthetic biology for the utilization of LAB as living therapeutics.</description><identifier>ISSN: 1226-8372</identifier><identifier>EISSN: 1976-3816</identifier><identifier>DOI: 10.1007/s12257-020-0033-6</identifier><language>eng</language><publisher>Seoul: The Korean Society for Biotechnology and Bioengineering</publisher><subject>Bacteria ; Biology ; Biotechnology ; Chemistry ; Chemistry and Materials Science ; Gene expression ; Genome editing ; Genomes ; Industrial and Production Engineering ; Lactic acid ; Lactic acid bacteria ; Medical treatment ; Review Paper ; Synthetic biology ; 생물공학</subject><ispartof>Biotechnology and Bioprocess Engineering, 2020, 25(6), , pp.962-973</ispartof><rights>The Korean Society for Biotechnology and Bioengineering and Springer 2020</rights><rights>The Korean Society for Biotechnology and Bioengineering and Springer 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-f2dacd286a82218b9151d0b9ebe529b7670d826945b8819a694b7e46337afe523</citedby><cites>FETCH-LOGICAL-c350t-f2dacd286a82218b9151d0b9ebe529b7670d826945b8819a694b7e46337afe523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12257-020-0033-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12257-020-0033-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002675700$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Son, Jaewoo</creatorcontrib><creatorcontrib>Jeong, Ki Jun</creatorcontrib><title>Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria</title><title>Biotechnology and bioprocess engineering</title><addtitle>Biotechnol Bioproc E</addtitle><description>Lactic acid bacteria (LAB) have a long historical record of usage in many types of food-related bioprocesses, and as LAB have been found to have intrinsic beneficial effects on human health, interest in using LAB as a medical treatment has increased. Moreover, recent advances in synthetic biology have enabled the engineering of so-called “smart” bacteria with the native characteristics of LAB. With various synthetic parts for gene expression, genome editing, and genetic circuits, gene expression can be precisely regulated in LAB. Moreover, LAB have been successfully developed as potential hosts for therapeutics to detect and control specific diseases or to deliver drug molecules. In this review, we outline the recent development of synthetic parts and approaches for the engineering of LAB. We also discuss the potential application of synthetic biology for the utilization of LAB as living therapeutics.</description><subject>Bacteria</subject><subject>Biology</subject><subject>Biotechnology</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Gene expression</subject><subject>Genome editing</subject><subject>Genomes</subject><subject>Industrial and Production Engineering</subject><subject>Lactic acid</subject><subject>Lactic acid bacteria</subject><subject>Medical treatment</subject><subject>Review Paper</subject><subject>Synthetic biology</subject><subject>생물공학</subject><issn>1226-8372</issn><issn>1976-3816</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kM1KAzEUhYMoWKsP4C7gysVofmaSzLItVQsFpdZ1yGQyY9qa1GQq9O3NOIIrV_dw7zmHywfANUZ3GCF-HzEhBc8QQRlClGbsBIxwyVlGBWanSRPCMkE5OQcXMW4QyrkQYgReVkYb18FJ_aWcNhFaB1-Prns3ndVwav3Ot0fY-ADTCs5da50xwboW-gYule5dE21rOE06HdQlOGvULpqr3zkGbw_z9ewpWz4_LmaTZaZpgbqsIbXSNRFMCUKwqEpc4BpVpalMQcqKM45qQViZF5UQuFRJVdzkjFKummShY3A79LrQyK220iv7M1svt0FOVuuFLFOL4Dh5bwbvPvjPg4md3PhDcOk9SXLOUF7SvG_Eg0sHH2MwjdwH-6HCUWIke8hygCwTZNlDlixlyJCJ-x6KCX_N_4e-ATFvfJk</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Son, Jaewoo</creator><creator>Jeong, Ki Jun</creator><general>The Korean Society for Biotechnology and Bioengineering</general><general>Springer Nature B.V</general><general>한국생물공학회</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7T7</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88A</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>L6V</scope><scope>LK8</scope><scope>M0C</scope><scope>M0S</scope><scope>M2P</scope><scope>M7P</scope><scope>M7S</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>Q9U</scope><scope>ACYCR</scope></search><sort><creationdate>20201201</creationdate><title>Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria</title><author>Son, Jaewoo ; Jeong, Ki Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-f2dacd286a82218b9151d0b9ebe529b7670d826945b8819a694b7e46337afe523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bacteria</topic><topic>Biology</topic><topic>Biotechnology</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Gene expression</topic><topic>Genome editing</topic><topic>Genomes</topic><topic>Industrial and Production Engineering</topic><topic>Lactic acid</topic><topic>Lactic acid bacteria</topic><topic>Medical treatment</topic><topic>Review Paper</topic><topic>Synthetic biology</topic><topic>생물공학</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Son, Jaewoo</creatorcontrib><creatorcontrib>Jeong, Ki Jun</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>ProQuest Central Basic</collection><collection>Korean Citation Index</collection><jtitle>Biotechnology and bioprocess engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Son, Jaewoo</au><au>Jeong, Ki Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria</atitle><jtitle>Biotechnology and bioprocess engineering</jtitle><stitle>Biotechnol Bioproc E</stitle><date>2020-12-01</date><risdate>2020</risdate><volume>25</volume><issue>6</issue><spage>962</spage><epage>973</epage><pages>962-973</pages><issn>1226-8372</issn><eissn>1976-3816</eissn><abstract>Lactic acid bacteria (LAB) have a long historical record of usage in many types of food-related bioprocesses, and as LAB have been found to have intrinsic beneficial effects on human health, interest in using LAB as a medical treatment has increased. Moreover, recent advances in synthetic biology have enabled the engineering of so-called “smart” bacteria with the native characteristics of LAB. With various synthetic parts for gene expression, genome editing, and genetic circuits, gene expression can be precisely regulated in LAB. Moreover, LAB have been successfully developed as potential hosts for therapeutics to detect and control specific diseases or to deliver drug molecules. In this review, we outline the recent development of synthetic parts and approaches for the engineering of LAB. We also discuss the potential application of synthetic biology for the utilization of LAB as living therapeutics.</abstract><cop>Seoul</cop><pub>The Korean Society for Biotechnology and Bioengineering</pub><doi>10.1007/s12257-020-0033-6</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1226-8372 |
| ispartof | Biotechnology and Bioprocess Engineering, 2020, 25(6), , pp.962-973 |
| issn | 1226-8372 1976-3816 |
| language | eng |
| recordid | cdi_nrf_kci_oai_kci_go_kr_ARTI_9670871 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Bacteria Biology Biotechnology Chemistry Chemistry and Materials Science Gene expression Genome editing Genomes Industrial and Production Engineering Lactic acid Lactic acid bacteria Medical treatment Review Paper Synthetic biology 생물공학 |
| title | Recent Advances in Synthetic Biology for the Engineering of Lactic Acid Bacteria |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T14%3A02%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_nrf_k&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recent%20Advances%20in%20Synthetic%20Biology%20for%20the%20Engineering%20of%20Lactic%20Acid%20Bacteria&rft.jtitle=Biotechnology%20and%20bioprocess%20engineering&rft.au=Son,%20Jaewoo&rft.date=2020-12-01&rft.volume=25&rft.issue=6&rft.spage=962&rft.epage=973&rft.pages=962-973&rft.issn=1226-8372&rft.eissn=1976-3816&rft_id=info:doi/10.1007/s12257-020-0033-6&rft_dat=%3Cproquest_nrf_k%3E2476049342%3C/proquest_nrf_k%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2476049342&rft_id=info:pmid/&rfr_iscdi=true |