The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration

ERBB4 is a member of the epidermal growth factor receptor (EGFR)/ERBB subfamily of receptor tyrosine kinases that regulates cellular processes including proliferation, migration, and survival. ERBB4 signaling is involved in embryogenesis and homeostasis of healthy adult tissues, but also in human pa...

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Veröffentlicht in:	The Journal of biological chemistry 2020-08, Vol.295 (33), p.11559-11571
Hauptverfasser:	Ojala, Veera K., Knittle, Anna M., Kirjalainen, Peppi, Merilahti, Johannes A.M., Kortesoja, Maarit, Tvorogov, Denis, Vaparanta, Katri, Lin, Shujun, Kast, Jürgen, Pulliainen, Arto T., Kurppa, Kari J., Elenius, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry & Molecular Biology breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology cancer cell migration Cell Movement ERBB4 Female guanine nucleotide exchange factor (GEF) HEK293 Cells HER4 Humans Life Sciences & Biomedicine MCF-7 Cells Mice NIH 3T3 Cells phosphotyrosine signaling Protein Interaction Maps protein-protein interaction Proto-Oncogene Proteins c-vav - metabolism receptor tyrosine kinase Receptor, ErbB-4 - metabolism Science & Technology Signal Transduction Vav guanine nucleotide exchange factor 3 (VAV3)
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