Recent advances in iron-complexes as drug candidates for cancer therapy: reactivity, mechanism of action and metabolites

In this perspective, we discuss iron-complexes as drug candidates that are promising alternatives to conventional platinum-based chemotherapies owing to their broad range of reactivities and to the targeting of different biological systems. Breakthroughs in the comprehension of iron complexes'...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2020-08, Vol.49 (33), p.11451-11466
Hauptverfasser:	Bouché, Mathilde, Hognon, Cécilia, Grandemange, Stéphanie, Monari, Antonio, Gros, Philippe C
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular structure Chemical Sciences Coordination compounds Homeostasis Iron Metabolites Platinum Reactivity Selectivity
Online-Zugang:	Volltext
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