Physiologic maturation is both extrinsically and intrinsically regulated in progenitor-derived neurons

During development, newly-differentiated neurons undergo several morphological and physiological changes to become functional, mature neurons. Physiologic maturation of neuronal cells derived from isolated stem or progenitor cells may provide insight into maturation in vivo but is not well studied....

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.2337-2337, Article 2337
Hauptverfasser:	Venugopalan, Praseeda, Cameron, Evan G., Zhang, Xiong, Nahmou, Michael, Muller, Kenneth J., Goldberg, Jeffrey L.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 13/51 14/34 14/63 38/77 38/90 631/378/2571/1696 631/378/2586 82/80 82/83 Aging Animals Calcium - metabolism Cells, Cultured Depolarization Developmental stages Dimerization Embryos gamma-Aminobutyric Acid - metabolism Humanities and Social Sciences Hyperpolarization K Cl- Cotransporters Maturation multidisciplinary Multidisciplinary Sciences Muscimol Neural stem cells Neurogenesis Potassium-chloride cotransporter Progenitor cells Rats Receptors, GABA-A - metabolism Retina Retinal ganglion cells Retinal Ganglion Cells - cytology Retinal Ganglion Cells - physiology Retinal Neurons - cytology Retinal Neurons - physiology Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Stem Cells - cytology Stem Cells - physiology Symporters - metabolism γ-Aminobutyric acid A receptors
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