Comparative analysis of fibrinolytic properties of Alteplase, Tenecteplase and Urokinase in an in vitro clot model of intracerebral haemorrhage

Hematoma lysis with recombinant tissue plasminogen activator (rtPA) has emerged as an alternative therapy for spontaneous intracerebral and intraventricular haemorrhage (ICH and IVH). However, the MISTIE III and CLEAR III trial failed to show significant improvement of favourable outcomes. Besides e...

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Veröffentlicht in:	Journal of stroke and cerebrovascular diseases 2020-09, Vol.29 (9), p.105073, Article 105073
Hauptverfasser:	Keric, Naureen, Döbel, Melanie, Krenzlin, Harald, Kurz, Elena, Tanyildizi, Yasemin, Heimann, Axel, König, Jochem, Kempski, Oliver, Ringel, Florian, Masomi-Bornwasser, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular System & Cardiology ICH IVH Life Sciences & Biomedicine lysis Neurosciences Neurosciences & Neurology Peripheral Vascular Disease rtPA Science & Technology Tenecteplase Urokinase
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