Syntheses and Applications of Singh’s Catalyst

Abstract Singh’s catalyst has emerged as one of the most promising and valuable catalysts in the field of asymmetric synthesis. Since its discovery, it has proven to be one of the best organocatalysts for asymmetric direct aldol reactions, and is equally efficient in aqueous and organic media. In this Short Review, we summarize reactions utilizing Singh’s catalyst under various conditions. 1 Introduction 2 Synthesis of Singh’s Catalyst 3 Applications in Asymmetric Synthesis 4 Conclusion