Testosterone‐androgen receptor: The steroid link inhibiting TRPM8‐mediated cold sensitivity

Recent studies have revealed gender differences in cold perception, and pointed to a possible direct action of testosterone (TST) on the cold‐activated TRPM8 (Transient Receptor Potential Melastatin Member 8) channel. However, the mechanisms by which TST influences TRPM8‐mediated sensory functions r...

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Veröffentlicht in:	The FASEB journal 2020-06, Vol.34 (6), p.7483-7499
Hauptverfasser:	Gkika, Dimitra, Lolignier, Stéphane, Grolez, Guillaume P., Bavencoffe, Alexis, Shapovalov, Georges, Gordienko, Dmitri, Kondratskyi, Artem, Meleine, Mathieu, Prival, Laetitia, Chapuy, Eric, Etienne, Monique, Eschalier, Alain, Shuba, Yaroslav, Skryma, Roman, Busserolles, Jérôme, Prevarskaya, Natalia
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - metabolism Animals Cell Line Cold Temperature Female Ganglia, Spinal - metabolism HEK293 Cells hormone Humans ion channel Life Sciences Male Membrane Proteins - metabolism Mice Mice, Inbred C57BL Neurons - metabolism Neurons and Cognition Pharmaceutical sciences Pharmacology Rats Rats, Wistar Receptors, Androgen - metabolism sensory neurons Testosterone - metabolism thermosensation transient receptor potential TRPM Cation Channels - metabolism
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