A Feedforward Loop within the Thyroid-Brown Fat Axis Facilitates Thermoregulation

Thyroid hormones (TH) control brown adipose tissue (BAT) activation and differentiation, but their subsequent homeostatic response following BAT activation remains obscure. This study aimed to investigate the relationship between cold- and capsinoids-induced BAT activation and TH changes between bas...

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Veröffentlicht in:	Scientific reports 2020-06, Vol.10 (1), p.9661-9661, Article 9661
Hauptverfasser:	Sun, Lijuan, Goh, Hui Jen, Govindharajulu, Priya, Sun, Lei, Henry, Christiani Jeyakumar, Leow, Melvin Khee-Shing
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443 692/163 Adipose tissue Adipose tissue (brown) Adipose Tissue, Brown - diagnostic imaging Adipose Tissue, Brown - metabolism Adult Body fat Calorimetry Capsaicin - administration & dosage Capsaicin - analogs & derivatives Capsaicin - pharmacology Cold Cold Temperature Cross-Over Studies Energy expenditure Exposure Feedback, Physiological Female Fluorodeoxyglucose F18 - administration & dosage Hormones Humanities and Social Sciences Humans Ingestion Male multidisciplinary Multidisciplinary Sciences Positron emission tomography Positron Emission Tomography Computed Tomography Science Science & Technology Science & Technology - Other Topics Science (multidisciplinary) Temperature Thermogenesis Thermogenesis - drug effects Thermoregulation Thyroid Thyroid gland Thyroid Gland - metabolism Thyroid hormones Thyroid-stimulating hormone Thyrotropin - blood Thyroxine Thyroxine - blood Triiodothyronine Triiodothyronine - blood Young Adult
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