RNA-sequencing reveals positional memory of multipotent mesenchymal stromal cells from oral and maxillofacial tissue transcriptomes

BackgroundMultipotent mesenchymal stromal cells (MSCs) can be isolated from numerous tissues and are attractive candidates for therapeutic clinical applications due to their immunomodulatory and pro-regenerative capacity. Although the minimum criteria for defining MSCs have been defined, their chara...

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Veröffentlicht in:	BMC genomics 2020-06, Vol.21 (1), p.417-417, Article 417
Hauptverfasser:	Onizuka, Satoru, Yamazaki, Yasuharu, Park, Sung-Joon, Sugimoto, Takayuki, Sone, Yumiko, Sjoqvist, Sebastian, Usui, Michihiko, Takeda, Akira, Nakai, Kenta, Nakashima, Keisuke, Iwata, Takanori
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigens Archives & records Biomedical materials Biotechnology & Applied Microbiology Bone marrow Cell adhesion & migration Cell cycle Cell Differentiation Cell Proliferation Cells, Cultured Craniofacial growth Defects Embryo cells Embryonic stem cells Gene expression Gene Expression Profiling - methods Gene Expression Regulation Gene Regulatory Networks Gene sequencing Genes Genetics & Heredity Genomics Health aspects High-Throughput Nucleotide Sequencing Homeodomain Proteins - genetics HOX genes Humans Iliac bone Ilium Ilium - chemistry Ilium - cytology Immunomodulation Jaw Life Sciences & Biomedicine Ligaments Mandible Mandible - chemistry Mandible - cytology Maxilla Maxilla - chemistry Maxilla - cytology Maxillofacial Maxillofacial bone Mesenchymal stem cells Mesenchymal Stem Cells - chemistry Mesenchymal Stem Cells - cytology Mesenchyme Multipotent mesenchymal stromal cells Organ Specificity Periodontal ligament Ribonucleic acid RNA RNA-sequencing Science & Technology Scientific equipment industry Sequence Analysis, RNA - methods Skin & tissue grafts Stem cells Stromal cells Therapeutic applications Tissues Whole Exome Sequencing
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