Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth With Elevated Blood Pressure

Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth With Elevated Blood Pressure

Hypertension is associated with cardiovascular events in adults. Subclinical changes to left ventricular strain and diastolic function have been found before development of decreased left ventricular ejection fraction and cardiovascular events. Our objective was to study effects of blood pressure (B...

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Veröffentlicht in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2020-06, Vol.75 (6), p.1551-1556
Hauptverfasser: Tran, Andrew H., Flynn, Joseph T., Becker, Richard C., Daniels, Stephen R., Falkner, Bonita E., Ferguson, Michael, Hanevold, Coral D., Hooper, Stephen R., Ingelfinger, Julie R., Lande, Marc B., Martin, Lisa J., Meyers, Kevin, Mitsnefes, Mark, Rosner, Bernard, Samuels, Joshua A., Urbina, Elaine M.
Format: Artikel
Sprache:eng
Schlagworte:
Adiposity - physiology
Adolescent
Asymptomatic Diseases - epidemiology
Blood Glucose - metabolism
Blood Pressure - physiology
Blood Pressure Determination - methods
Blood Pressure Determination - statistics & numerical data
Cardiometabolic Risk Factors
Cardiovascular System & Cardiology
Child
Echocardiography - methods
Female
Humans
Hypertension - blood
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - physiopathology
Life Sciences & Biomedicine
Male
Peripheral Vascular Disease
Science & Technology
Stroke Volume
United States - epidemiology
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:Hypertension is associated with cardiovascular events in adults. Subclinical changes to left ventricular strain and diastolic function have been found before development of decreased left ventricular ejection fraction and cardiovascular events. Our objective was to study effects of blood pressure (BP) on ventricular function in youth across the BP spectrum. Vital signs and labs were obtained in 346 participants aged 11 to 19 years who had BP categorized as low-risk (N=144; systolic BP
ISSN:0194-911X
1524-4563
DOI:10.1161/HYPERTENSIONAHA.119.14682