Efficient and Divergent Enantioselective Syntheses of DHPVs and Anti-Inflammatory Effect on IEC-6 Cells

Despite numerous reports on the beneficial effects of catechin or epicatechin contained in tea and cacao extract on human health, a conclusive and precise molecular mechanism has not been elucidated. Metabolism of chemical compounds in gut microbiota recently gained significant attention, and extens...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2020-05, Vol.25 (9), p.2215, Article 2215
Hauptverfasser:	Kim, Hyun Su, Chung, Sungkyun, Song, Moon-Young, Lim, Changjin, Shin, Hyeyoung, Hur, Joonseong, Kwon, Hyuk, Suh, Young-Ger, Kim, Eun-Hee, Shin, Dongyun, Kim, Seok-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory agents Anti-Inflammatory Agents - chemical synthesis Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology anti-inflammatory effect asymmetric dihydroxylation Biochemistry & Molecular Biology Catechin Cell Line Chemical compounds Chemistry Chemistry, Multidisciplinary Chirality DHPV Digestive system Divergence divergent synthesis Enantiomers Epicatechin Inflammation Inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - drug therapy Inflammatory Bowel Diseases - metabolism Inflammatory Bowel Diseases - pathology Intestinal microflora Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestine IκBα Lactones - chemical synthesis Lactones - chemistry Lactones - pharmacology Life Sciences & Biomedicine Medical treatment Metabolism Metabolites Metathesis Microbiota NF-κB Phosphorylation Physical Sciences Polyphenols Rats Science & Technology Tea
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