Dosimetric and radiobiological comparison of simultaneous integrated boost and sequential boost of locally advanced cervical cancer

•Simultaneous integrated boost can be an effective treatment for cervical cancer patients ineligible for brachytherapy.•Simultaneous integrated boost is dosimetrically and radiobiologically more effective than sequential boost.•Implementation of simultaneous integrated boost saves at least a week of...

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Veröffentlicht in:	Physica medica 2020-05, Vol.73, p.83-88
Hauptverfasser:	Sukhikh, E.S., Sukhikh, L.G., Lushnikova, P.A., Tatarchenko, M.A., Abdelrahman, Ahmed Ramadan
Format:	Artikel
Sprache:	eng
Schlagworte:	Female Humans Locally advanced cervical cancer NTCP Organs at Risk - radiation effects Radiobiology Radiometry Radiotherapy Dosage Radiotherapy, Intensity-Modulated - adverse effects Radiotherapy, Intensity-Modulated - methods Simultaneous integrated boost TCP Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - radiotherapy Volumetric modulated arc therapy
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