Biointerface topography regulates phenotypic switching and cell apoptosis in vascular smooth muscle cells

In-stent restenosis (ISR) is a complex disease that occurs after coronary stenting procedures. The development of quality materials and improvement of our understanding on significant factors regulating ISR are essential for enhancing prognosis. Vascular smooth muscle cells (VSMCs) are the main cons...

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Veröffentlicht in:	Biochemical and biophysical research communications 2020-06, Vol.526 (3), p.841-847
Hauptverfasser:	Han, Lu, Yin, Qingde, Yang, Liangliang, van Rijn, Patrick, Yang, Yanyan, Liu, Yan, Li, Min, Yan, Mingzhe, Zhou, Qihui, Yu, Tao, Lian, Zhexun
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Actins - metabolism Apoptosis Biochemistry & Molecular Biology Biomechanical Phenomena Biophysics Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Calponins Caspase 3 - genetics Caspase 3 - metabolism Cell Line Cell Proliferation Cells, Cultured Cross-Linking Reagents - chemistry Dimethylpolysiloxanes - chemistry Gene Expression Regulation Humans In-stent restenosis Life Sciences & Biomedicine Major Histocompatibility Complex - genetics Microfilament Proteins - genetics Microfilament Proteins - metabolism Microscopy, Atomic Force Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Phenotype Phenotypic switching Polydimethylsiloxane Science & Technology Surface Properties Tissue Scaffolds - chemistry Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Vascular smooth muscle cells Wrinkled topography
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