Hospitalization Before Liver Transplantation Predicts Posttransplant Patient Survival: A Propensity Score–Matched Analysis

In contrast to donor factors predicting outcomes of liver transplantation (LT), few suitable recipient parameters have been identified. To this end, we performed an in‐depth analysis of hospitalization status and duration prior to LT as a potential risk factor for posttransplant outcome. The pretran...

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Veröffentlicht in:Liver transplantation 2020-05, Vol.26 (5), p.628-639
Hauptverfasser: Wiering, Leke, Öllinger, Robert, Kruppa, Jochen, Schoeneberg, Uwe, Dziodzio, Tomasz, Jara, Maximillian, Biebl, Matthias, Dargie, Richard, Raschzok, Nathanael, Schöning, Wenzel, Eurich, Dennis, Schmelzle, Moritz, Sauer, Igor M., Pratschke, Johann, Ritschl, Paul V.
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Sprache:eng
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Zusammenfassung:In contrast to donor factors predicting outcomes of liver transplantation (LT), few suitable recipient parameters have been identified. To this end, we performed an in‐depth analysis of hospitalization status and duration prior to LT as a potential risk factor for posttransplant outcome. The pretransplant hospitalization status of all patients undergoing LT between 2005 and 2016 at the Charité‐Universitätsmedizin Berlin was analyzed retrospectively using propensity score matching. At the time of organ acceptance, 226 of 1134 (19.9%) recipients were hospitalized in an intensive care unit (ICU), 146 (12.9%) in a regular ward (RW) and 762 patients (67.2%) were at home. Hospitalized patients (RW and ICU) compared with patients from home showed a dramatically shorter 3‐month survival (78.7% versus 94.4%), 1‐year survival (66.3% versus 87.3%), and 3‐year survival (61.7% versus 81.7%; all P 14 days, 60.5% versus 51.0%, P = 0.006). In conclusion, hospitalization status before transplantation is a valuable predictor of patient survival following LT.
ISSN:1527-6465
1527-6473
DOI:10.1002/lt.25748