Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension

Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 0...

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Veröffentlicht in:Pulmonary circulation 2020-01, Vol.10 (1), p.1-5
Hauptverfasser: Richter, Manuel J., Harutyunova, Satenik, Bollmann, Tom, Classen, Simon, Fuge, Jan, Gall, Henning, Gerhardt, Felix, Ghofrani, Hossein A., Gunkel, Hartmut, Grünig, Ekkehard, Halank, Michael, Heine, Alexander, Klose, Hans, Lange, Tobias J., Neurohr, Claus, Nickolaus, Kai, Opitz, Christian F., Rosenkranz, Stephan, Seyfarth, Hans-Jürgen, Tello, Khodr, Ewert, Ralf, Olsson, Karen M.
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Sprache:eng
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Zusammenfassung:Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.
ISSN:2045-8940
2045-8932
2045-8940
DOI:10.1177/2045894020910136