Experience with provisional WHO‐entities large B‐cell lymphoma with IRF4‐rearrangement and Burkitt‐like lymphoma with 11q aberration in paediatric patients of the NHL‐BFM group

Summary Large B‐cell lymphoma with IRF4 rearrangement, and Burkitt‐like lymphoma with 11q aberration are two provisional lymphoma entities in the 2017 revision of the WHO classification of lymphoid neoplasms. Despite being more frequent in young patients, knowledge regarding their true incidence and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 2020-09, Vol.190 (5), p.753-763
Hauptverfasser:	Au‐Yeung, Rex K. H., Arias Padilla, Laura, Zimmermann, Martin, Oschlies, Ilske, Siebert, Reiner, Woessmann, Wilhelm, Burkhardt, Birgit, Klapper, Wolfram
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent B cells Burkitt Lymphoma - genetics Burkitt Lymphoma - mortality Burkitt's lymphoma Child Child, Preschool chromosome 11q Chromosome Aberrations Chromosomes, Human, Pair 11 Clinical trials Disease-Free Survival Female Fluorescence in situ hybridization Gene Rearrangement Hematology Humans Interferon regulatory factor 4 Interferon Regulatory Factors - genetics Lymphoma Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - mortality Male Myc protein Neoplasm Proteins - genetics Non-Hodgkin's lymphoma non‐Hodgkin lymphoma paediatric haematology paediatric oncology Pediatrics Survival Rate World Health Organization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Summary Large B‐cell lymphoma with IRF4 rearrangement, and Burkitt‐like lymphoma with 11q aberration are two provisional lymphoma entities in the 2017 revision of the WHO classification of lymphoid neoplasms. Despite being more frequent in young patients, knowledge regarding their true incidence and clinical features in unselected cohorts of paediatric and adolescent patients is limited. We screened for both entities among paediatric patients (
ISSN:	0007-1048 1365-2141
DOI:	10.1111/bjh.16578