Intratympanic gentamycine for Ménière’s disease: is there a selective vestibulotoxic effect?

Purpose The aim of our study is to investigate the effectiveness and safety of the treatment, based on vertigo diaries and pure tone audiograms. Methods The complete medical documentation of 105 definite patients suffering from Ménière’s disease was analyzed. In the studied group, nine patients were...

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Veröffentlicht in:European archives of oto-rhino-laryngology 2020-07, Vol.277 (7), p.1949-1954
Hauptverfasser: Molnár, András, Maihoub, Stefani, Gáborján, Anita, Tamás, László, Szirmai, Ágnes
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Sprache:eng
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Zusammenfassung:Purpose The aim of our study is to investigate the effectiveness and safety of the treatment, based on vertigo diaries and pure tone audiograms. Methods The complete medical documentation of 105 definite patients suffering from Ménière’s disease was analyzed. In the studied group, nine patients were treated with intratympanic gentamycine. Long-term follow-up of the patients was carried out, using vertigo diaries, medical letters, anamnestic data, and pure tone audiograms. Audiometric results and vertigo complaints before and after treatment were contrasted using IBM SPSS V24 software. Results Based on our analysis, vertigo attacks appeared significantly less often after gentamycine treatment [ p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-020-05901-3