Platelet Adhesion and Thrombus Formation in Microchannels: The Effect of Assay-Dependent Variables

Microfluidic flow chambers (MFCs) allow the study of platelet adhesion and thrombus formation under flow, which may be influenced by several variables. We developed a new MFC, with which we tested the effects of different variables on the results of platelet deposition and thrombus formation on a co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2020-01, Vol.21 (3), p.750
Hauptverfasser:	Scavone, Mariangela, Bozzi, Silvia, Mencarini, Tatiana, Podda, Gianmarco, Cattaneo, Marco, Redaelli, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylsalicylic acid Adhesion Adhesives Aggregates antiplatelet agents Blood Blood clots Blood platelets Coatings Collagen Collagen (type I) Cyclooxygenase-1 Dependent variables Deposition Drugs Experiments flow assays Flow chambers Low concentrations Microchannels Microfluidics Morphology Perfusion platelet adhesion platelet aggregation platelets Reagents Room temperature Shear rate Statistical analysis Statistical methods Storage temperature Thrombosis thrombus formation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!