PKM2 upregulation promotes malignancy and indicates poor prognosis for intrahepatic cholangiocarcinoma

•I wish to submit an original article for publication in Clinics and Research in Hepatology and Gastroenterology, titled “PKM2 upregulation diminishes malignancy and indicates good prognosis for intrahepatic cholangiocarcinoma”.•Although pyruvate kinase M2 (PKM2) has been shown to be among the cruci...

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Veröffentlicht in:	Clinics and research in hepatology and gastroenterology 2020-04, Vol.44 (2), p.162-173
Hauptverfasser:	Qian, Ze, Hu, Wendi, Lv, Zhen, Liu, Hua, Chen, Diyu, Wang, Yacong, Wu, Jian, Zheng, Shusen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bile Duct Neoplasms - etiology Bile Duct Neoplasms - mortality Bile Duct Neoplasms - pathology Carrier Proteins - physiology Cell proliferation Cholangiocarcinoma - etiology Cholangiocarcinoma - mortality Cholangiocarcinoma - pathology Female Gastroenterology & Hepatology Humans Intrahepatic cholangiocarcinoma Life Sciences & Biomedicine Male Membrane Proteins - physiology Middle Aged Migration Prognosis Pyruvate kinase Science & Technology Survival Rate Thyroid Hormone-Binding Proteins Thyroid Hormones - physiology Up-Regulation
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