Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells

Multidrug resistance (MDR) is a critical hindrance to the success of cancer chemotherapy. The main thing responsible for MDR phenotypes are plasma-membranes associated with adenosine triphosphate (ATP) Binding Cassette (ABC) drug efflux transporters, such as the P-glycoprotein (Pgp) transporter that...

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Veröffentlicht in:Pharmaceutics 2020-01, Vol.12 (2), p.96, Article 96
Hauptverfasser: Fathy Abd-Ellatef, Gamal-Eldein, Gazzano, Elena, Chirio, Daniela, Ragab Hamed, Ahmed, Belisario, Dimas Carolina, Zuddas, Carlo, Peira, Elena, Rolando, Barbara, Kopecka, Joanna, Assem Said Marie, Mohamed, Sapino, Simona, Ramadan Fahmy, Sohair, Gallarate, Marina, Zaki Abdel-Hamid, Abdel-Hamid, Riganti, Chiara
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