The effect of percutaneous transforaminal endoscopic discectomy (PTED) on serum inflammatory factors and pain in patients with lumbar disc herniation after surgery

The effect of percutaneous transforaminal endoscopic discectomy (PTED) on serum inflammatory factors and pain in patients with lumbar disc herniation after surgery

Objective: The study aims to investigate the effect of PTED on serum inflammatory factors and pain in patients with lumbar disc herniation. Methods: 94 patients with lumbar disc herniation treated in our hospital were enrolled in this study. Patients were randomly divided into group A (n=47) and gro...

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Veröffentlicht in:International journal of clinical and experimental medicine 2020-01, Vol.13 (2), p.597-603
Hauptverfasser: Dai, Hongjie, Zhang, Xu, Wang, Litao, Jin, Xianhui, Cui, Xiaolei, Cui, Shengjie
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container_issue 2
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container_title International journal of clinical and experimental medicine
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creator Dai, Hongjie
Zhang, Xu
Wang, Litao
Jin, Xianhui
Cui, Xiaolei
Cui, Shengjie
description Objective: The study aims to investigate the effect of PTED on serum inflammatory factors and pain in patients with lumbar disc herniation. Methods: 94 patients with lumbar disc herniation treated in our hospital were enrolled in this study. Patients were randomly divided into group A (n=47) and group B (n=47). Group A were treated with fenestration discectomy, and Group B were treated with PTED discectomy. The general clinical data, the duration of surgery, bleeding amount, the length of hospital stay, and the complications of patients were compared between two groups. The serum level of TNF-a and IL-6 was detected by enzyme-linked immunosorbent assay (ELISA), and the visual an-alogue score (VAS) between group A and group B was compared by Japanese Orthopaedic Association Scores (JOA). Results: The total duration of surgery, total bleeding amount, and length of hospital stay in group B were less or shorter than those in group A (P
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Methods: 94 patients with lumbar disc herniation treated in our hospital were enrolled in this study. Patients were randomly divided into group A (n=47) and group B (n=47). Group A were treated with fenestration discectomy, and Group B were treated with PTED discectomy. The general clinical data, the duration of surgery, bleeding amount, the length of hospital stay, and the complications of patients were compared between two groups. The serum level of TNF-a and IL-6 was detected by enzyme-linked immunosorbent assay (ELISA), and the visual an-alogue score (VAS) between group A and group B was compared by Japanese Orthopaedic Association Scores (JOA). Results: The total duration of surgery, total bleeding amount, and length of hospital stay in group B were less or shorter than those in group A (P&lt;0.001). The TNF-alpha level, IL-6 level and VAS score after treatment in group B were lower than those in group A (P&lt;0.001). While the JOA score in group B was higher than that in group A (P&lt;0.001); the incidence of adverse complications such as lumbar deformation, aggravate pain and postoperative distasia in group B was lower than that in group A (P&gt;0.05). The quality of life scores in group B were higher than those in group A (P&lt;0.001). Conclusion: In summary, PTED has a better effect on the disease control and pain relief in patients with lumbar disc herniation; it has played a greater role in improving patients' quality of life, which is worthy of clinical promotion.</description><identifier>ISSN: 1940-5901</identifier><identifier>EISSN: 1940-5901</identifier><language>eng</language><publisher>MADISON: E-Century Publishing Corp</publisher><subject>Life Sciences &amp; Biomedicine ; Medicine, Research &amp; Experimental ; Research &amp; Experimental Medicine ; Science &amp; Technology</subject><ispartof>International journal of clinical and experimental medicine, 2020-01, Vol.13 (2), p.597-603</ispartof><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>2</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000518397600031</woscitedreferencesoriginalsourcerecordid><cites>FETCH-webofscience_primary_0005183976000313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,28253</link.rule.ids></links><search><creatorcontrib>Dai, Hongjie</creatorcontrib><creatorcontrib>Zhang, Xu</creatorcontrib><creatorcontrib>Wang, Litao</creatorcontrib><creatorcontrib>Jin, Xianhui</creatorcontrib><creatorcontrib>Cui, Xiaolei</creatorcontrib><creatorcontrib>Cui, Shengjie</creatorcontrib><title>The effect of percutaneous transforaminal endoscopic discectomy (PTED) on serum inflammatory factors and pain in patients with lumbar disc herniation after surgery</title><title>International journal of clinical and experimental medicine</title><addtitle>INT J CLIN EXP MED</addtitle><description>Objective: The study aims to investigate the effect of PTED on serum inflammatory factors and pain in patients with lumbar disc herniation. Methods: 94 patients with lumbar disc herniation treated in our hospital were enrolled in this study. Patients were randomly divided into group A (n=47) and group B (n=47). Group A were treated with fenestration discectomy, and Group B were treated with PTED discectomy. The general clinical data, the duration of surgery, bleeding amount, the length of hospital stay, and the complications of patients were compared between two groups. The serum level of TNF-a and IL-6 was detected by enzyme-linked immunosorbent assay (ELISA), and the visual an-alogue score (VAS) between group A and group B was compared by Japanese Orthopaedic Association Scores (JOA). Results: The total duration of surgery, total bleeding amount, and length of hospital stay in group B were less or shorter than those in group A (P&lt;0.001). The TNF-alpha level, IL-6 level and VAS score after treatment in group B were lower than those in group A (P&lt;0.001). While the JOA score in group B was higher than that in group A (P&lt;0.001); the incidence of adverse complications such as lumbar deformation, aggravate pain and postoperative distasia in group B was lower than that in group A (P&gt;0.05). The quality of life scores in group B were higher than those in group A (P&lt;0.001). 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Methods: 94 patients with lumbar disc herniation treated in our hospital were enrolled in this study. Patients were randomly divided into group A (n=47) and group B (n=47). Group A were treated with fenestration discectomy, and Group B were treated with PTED discectomy. The general clinical data, the duration of surgery, bleeding amount, the length of hospital stay, and the complications of patients were compared between two groups. The serum level of TNF-a and IL-6 was detected by enzyme-linked immunosorbent assay (ELISA), and the visual an-alogue score (VAS) between group A and group B was compared by Japanese Orthopaedic Association Scores (JOA). Results: The total duration of surgery, total bleeding amount, and length of hospital stay in group B were less or shorter than those in group A (P&lt;0.001). The TNF-alpha level, IL-6 level and VAS score after treatment in group B were lower than those in group A (P&lt;0.001). While the JOA score in group B was higher than that in group A (P&lt;0.001); the incidence of adverse complications such as lumbar deformation, aggravate pain and postoperative distasia in group B was lower than that in group A (P&gt;0.05). The quality of life scores in group B were higher than those in group A (P&lt;0.001). Conclusion: In summary, PTED has a better effect on the disease control and pain relief in patients with lumbar disc herniation; it has played a greater role in improving patients' quality of life, which is worthy of clinical promotion.</abstract><cop>MADISON</cop><pub>E-Century Publishing Corp</pub><tpages>7</tpages></addata></record>
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subjects Life Sciences & Biomedicine
Medicine, Research & Experimental
Research & Experimental Medicine
Science & Technology
title The effect of percutaneous transforaminal endoscopic discectomy (PTED) on serum inflammatory factors and pain in patients with lumbar disc herniation after surgery
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