Impact of T(h)1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques

Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (T-fh) cells with germinal center (GC) B cells. T(h)1 polarization of T-fh cells is an important process shaping the success of T-fh-GC B cell interactions by influencing costimulatory...

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Veröffentlicht in:Journal of virology 2020-03, Vol.94 (6), Article 01737
Hauptverfasser: Verma, Anil, Schmidt, Brian A., Elizaldi, Sonny R., Nguyen, Nancy K., Walter, Korey A., Beck, Zoltan, Trinh, Hung, Dinasarapu, Ashok R., Lakshmanappa, Yashavanth Shaan, Rane, Niharika N., Matyas, Gary R., Rao, Mangala, Shen, Xiaoying, Tomaras, Georgia D., LaBranche, Celia C., Reimann, Keith A., Foehl, David H., Gach, Johannes S., Forthal, Donald N., Kozlowski, Pamela A., Amara, Rama R., Iyer, Smita S.
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Sprache:eng
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