Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine H-1-MR spectroscopy study

It is unclear whether alterations in cerebral pH underlie Alzheimer's disease (AD) and other dementias. We performed proton spectroscopy after oral administration of histidine in healthy young and elderly persons and in patients with mild cognitive impairment and dementia (total N = 147). We me...

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Veröffentlicht in:	Neurobiology of aging 2020-03, Vol.87, p.60-69
Hauptverfasser:	Lyros, Epameinondas, Ragoschke-Schumm, Andreas, Kostopoulos, Panagiotis, Sehr, Alexandra, Backens, Martin, Kalampokini, Stefania, Decker, Yann, Lesmeister, Martin, Liu, Yang, Reith, Wolfgang, Fassbender, Klaus
Format:	Artikel
Sprache:	eng
Schlagworte:	Geriatrics & Gerontology Life Sciences & Biomedicine Neurosciences Neurosciences & Neurology Science & Technology
Online-Zugang:	Volltext
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