A Versatile ES Cell-Based Melanoma Mouse Modeling Platform

The cumbersome and time-consuming process of generating new mouse strains and multiallelic experimental animals often hinders the use of genetically engineered mouse models (GEMM) in cancer research. Here, we describe the development and validation of an embryonic stem cell (ESC)-GEMM platform for r...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2020-02, Vol.80 (4), p.912-921
Hauptverfasser:	Bok, Ilah, Vera, Olga, Xu, Xiaonan, Jasani, Neel, Nakamura, Koji, Reff, Jordan, Nenci, Arianna, Gonzalez, Jose G., Karreth, Florian
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences & Biomedicine Oncology Science & Technology
Online-Zugang:	Volltext
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