Extracellular signal-regulated kinases 1 and 2 regulate neuromuscular junction and myofiber phenotypes in mammalian skeletal muscle

•ERK1/2 signaling regulates neuromuscular synapse-specific transcription.•ERK1/2 signaling regulates acquisition and maintenance of slow myofiber phenotype.•ERK1/2 signaling may control muscle progenitor role after nerve injury and aging. The neuromuscular junction is the synapse between a motor neu...

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