Amphiphilic PLGA‐PEG‐PLGA triblock copolymer nanogels varying in gelation temperature and modulus for the extended and controlled release of hyaluronic acid

ABSTRACT Different compositional parameters of poly(D,L‐lactic‐co‐glycolic acid)‐b‐poly(ethylene glycol) triblock copolymers (PLGA‐PEG) were varied to analyze their effect on gel formation and mechanical properties. Parameters such as hydrophilic/hydrophobic ratio (PLGA/PEG ratio), lactic acid/glyco...

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Veröffentlicht in:	Journal of applied polymer science 2020-07, Vol.137 (25), p.n/a, Article 48678
Hauptverfasser:	Osorno, Laura L., Maldonado, Daniel E., Whitener, Ricky J., Brandley, Alyssa N., Yiantsos, Alex, Medina, Jamie D. R., Byrne, Mark E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Block copolymers Controlled release Copolymers Gelation Glycolic acid Hyaluronic acid Hydrogels Lactic acid Lysine Materials science Mechanical properties Molecular weight Parameters Physical Sciences Polydispersity Polyethylene glycol Polymer Science Polymers Science & Technology
Online-Zugang:	Volltext
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