Over-expression of heme oxygenase-1 in peripheral blood predicts the progression and relapse risk of chronic myeloid leukemia

Background There are limited eligible clinical markers at present to monitor the progress of chronic myeloid leukemia （CML）.Heme oxygenase-1 （HO-1）,as one of the most important oxidation-regulating enzymes in vivo,suggests the onset and progression of cancer when highly expressed.Furthermore,HO-1 le...

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Veröffentlicht in:	Chinese medical journal 2014, Vol.127 (15), p.2795-2801
Hauptverfasser:	Wei, Sixi, Wang, Yating, Chai, Qixiang, Fang, Qin, Zhang, Yaming, Lu, Yinghao, Wang, Jishi
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Marrow - metabolism Female Flow Cytometry Gene Expression Heme Oxygenase-1 - blood Heme Oxygenase-1 - genetics Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Male Predictive Value of Tests Real-Time Polymerase Chain Reaction 复发外周血慢性粒细胞白血病血红素加氧酶-1 血红素氧合酶-1 过表达预测风险
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